GBS urine infection

Although most microbiology laboratories do not routinely test for GBS in the urine, if it is cultured at any time during the current pregnancy, there is a higher risk of neonatal disease. It is possible that detected urinary tract infections indicate a higher level of genital tract GBS carriage. Exact quantification of the risk of neonatal disease is not possible, but in addition to treatment of the urinary infection at the time of diagnosis, after discussion, intrapartum prophylaxis should be offered.

	Intrapartum IV antibiotic prophylaxis should be offered to women with GBS bacteriuria in the current pregnancy

Penicillin 3g IV as soon as possible after the onset of labour
followed by
Penicillin 1.5g IV four-hourly until delivery
Or, in the case of penicillin sensitivity,
Clindamycin 900mg IV eight-hourly